小儿肾炎和肾病是儿科常见病。解放初期病死率在30%以上,以后由于应用抗菌素有效地控制感染,以及肾上腺皮质激素和中西医结合治疗,病死率下降到15%左右,七十年代以来,加用免疫抑制剂使病死率进一步下降到3%以下。但是,仍有相当一部分病例,尤其原发性肾病综合征的肾炎型和某些继发性肾病综合征,临床上应用肾上腺皮质激素治疗,对初治、再治或始终治疗无反应的难治性肾病综合征病人,病程迁延反复,治疗效果不够理想,甚至最后发展为肾功能衰竭,应当值得我们重视。 Pediatric nephritis and nephropathy are common pediatric diseases. In the early liberation mortality rate of 30% or more, since the effective use of antibiotics to control infection, and adrenal cortex hormones and traditional Chinese and Western medicine treatment, mortality dropped to about 15%, since the seventies, plus immunosuppressive agents further mortality Drop to below 3%. However, there are still a considerable number of cases, especially nephritis of primary nephrotic syndrome and some secondary nephrotic syndromes, clinically adrenocorticotropic hormone therapy, refractory to initial treatment, re-treatment, or always treatment Patients with nephrotic syndrome, repeated protracted course of disease, the treatment effect is not ideal, and even eventually developed into renal failure, it deserves our attention.