腰痛/血尿综合征表现为复发性单侧或双侧腰痛伴肉眼或镜下血尿。肾活检常显示小动脉壁大量 C_3呈颗粒状沉着,血管造影可发现肾内血管异常。对患此征患者给予皮下注射回忆抗原,出现型超敏反应增强,提示此综合征可能是一种超敏反应状态。本文作者对8例此综合征患者使用能引起皮肤反应的抗原,进行细胞和体液免疫应答体外研究。诊断以临床和肾活检所见为依据,观察此综合征患者和4名正常自愿者,在免疫应答过程中 T 细胞增生和血清抗体水平,以及 T 细胞表型,结果以刺激指数表示。T 细胞增生在患者与对照者之间没有差异。虽然有3例患者 T_3计数降低,但作为患者和对照两组之间没有差异,T_4/T_3比值亦无差异。所有患者和对照者的血清中都出现抗人和抗牛 PPD 抗体,平均吸收值没有差异。皮肤与体外应答之间,或体外应答与 Low back pain / hematuria syndrome manifested as recurrent unilateral or bilateral low back pain with gross or microscopic hematuria. Renal biopsy often shows a large number of small artery wall was granular C_3 angiography can be found in renal vascular abnormalities. Patients suffering from this syndrome were given subcutaneous injection of memory antigen, increased type hypersensitivity, suggesting that the syndrome may be a hypersensitivity state. In this study, eight patients with this syndrome were challenged with a cell-derived and humoral immune response in vitro using antigens that cause skin reactions. The diagnosis was based on clinical and renal biopsy findings. Patients with this syndrome and 4 normal volunteers were observed for T cell proliferation and serum antibody levels during immune response, as well as T cell phenotypes and results were expressed as stimulation indices. T cell proliferation did not differ between patients and controls. Although there was a decrease in T_3 count in 3 patients, there was no difference between the two groups as a control group and no difference in T_4 / T_3 ratio. Anti-human and anti-bovine PPD antibodies appeared in the sera of all patients and controls with no difference in mean absorption values. Between skin and in vitro response, or in vitro response with