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该文对实验大鼠进行单价肾综合征出血热灭活疫苗免疫,结果表明免疫大鼠能产生较高的同型和异型中和抗体及IFA抗体应答,因而,大鼠可以作为疫苗效力评价的实验动物.“,”Laboratory rats were vaccinated with an monovalent inactivated vaccine for HFRS to observe the immune responses. The immunized sera were detected by plaque reduction neutralization test and IFA. The result indicated that the vaccine could induce effective homologous and heterologous neutralizing antibody and IFA antibody responses in laboratory rats. Laboratory rat may be used as the animal for evaluating vaccine effect.