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人和动物肿瘤的发生发展就细胞而言,是由于原癌基因的激活和抑癌基因的失活而造成的,所以癌基因与抑癌基因的研究对探索肿瘤发病机理,寻找预防和治疗肿瘤的新措施都具有重要意义.卵巢癌在妇科恶性肿瘤中以难治著称,不易早期发现,且存活率低.目前人类对卵巢癌的遗传基础认识仍然不很清楚,许多研究表明卵巢癌的发生涉及一系列基因的变化,包括显性癌基因、错配修复基因和众多的肿瘤抑制基因.mRNA差异显示方法因其简单、敏感、高效、快速等
The development of human and animal tumors in terms of cells, is due to activation of proto-oncogene and tumor suppressor gene inactivation caused, so oncogene and tumor suppressor gene research to explore the pathogenesis of cancer, looking for the prevention and treatment of cancer Of the new measures are of great significance.Ovarian cancer in gynecological malignancies known as refractory, not easy to find early, and low survival rate.Now the human genetic basis for ovarian cancer is still not clear, many studies have shown that the occurrence of ovarian cancer Involved in a series of gene changes, including dominant oncogenes, mismatch repair genes and a large number of tumor suppressor genes.mRNA differential display method because of its simple, sensitive, efficient, fast, etc.