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目的探讨前哨淋巴结活检(SLNB)预测腋窝淋巴结肿瘤转移的临床价值。方法选取四平市中心人民医院收治的72例乳腺癌患者作为研究对象,均经体检证明无腋窝淋巴结转移,使用亚甲蓝皮下注射染色法对前哨淋巴结(SLN)进行定位,根据病理检查结果对SLNB的成功率、假阴性率、假阳性率、阳性符合率、准确度等进行计算。结果 SLN检出成功率为98.6%,灵敏度为91.7%,特异度为98.3%,准确度为97.2%,阳性预测值为91.7%,阴性预测值为98.3%。结论运用亚甲蓝皮下注射染色法进行SLNB,能提高检出成功率,并对腋窝淋巴结有无肿瘤转移情况进行准确预测。
Objective To investigate the clinical value of sentinel lymph node biopsy (SLNB) in prediction of axillary lymph node metastasis. Methods Seventy-two breast cancer patients admitted to People’s Hospital of Siping City were selected as the study subjects. All patients were confirmed by physical examination without axillary lymph node metastasis. SLN was localized by methylene blue subcutaneous injection staining. According to the results of pathological examination, SLNB The success rate, false negative rate, false positive rate, positive coincidence rate, accuracy and so on. Results The success rate of SLN detection was 98.6%, the sensitivity was 91.7%, the specificity was 98.3%, the accuracy was 97.2%, the positive predictive value was 91.7% and the negative predictive value was 98.3%. Conclusion The subcutaneous injection of methylene blue staining for SLNB can improve the detection success rate and accurately predict axillary lymph node metastasis.