Locoweed is one of main poisonous plants in the world, and also is the most important toxic plant in grassland of China. The distribution range of the locoweed is extending continuously and it has formed or is coming into dominant species gradually in some areas in recent years, which cause the retrogressive succession and grazer poisoning and died in rangeland. Locoweed seriously threatened the grassland agriculture and made typical ’ecology-economic sick’ in above district. Based on the investigation, research, prevention and cure practice to the locoweed for more than ten years, this paper reviewed the present situation and prospect of the studies on the locoweed in China, which include the researches of it’s biological characteristics, distribution, ecological environment, harmfulness, prevention, weeding, utilization and ecological control etc. Locoweed is one of main poisonous plants in the world, and also the the most important toxic plant in grassland of China. The distribution range of the locoweed is extending continuously and it has formed or is coming into dominant species gradually in some areas in recent years based on the investigation, research, prevention and cure practice to the locoweed for more than ten years, this paper reviewed the present situation and prospect of the studies on the locoweed in china, which include the researches of it’s biological characteristics, distribution, ecological environment, harmfulness, prevention, weeding, utilization and ecological control etc.