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血浆儿茶酚胺的测定对嗜铬细胞瘤诊断和定位是一种最敏感和最可靠的方法。其诊断标准：静息卧位血浆去甲肾上腺素＞１１．８２ｐｍｏｌ／ｍｌ及／或肾上腺素＞５．４６ｐｍｏｌ／ｍｌ。肿瘤主要以持续弥散方式释放儿茶酚胺，根据其释放量，可分为多分泌型与少或不分泌型。血浆儿茶酚胺浓度取决于肿瘤分泌会，而与肿瘤大小和儿茶酚胺总含量无关。腔静脉分段取血定位肿瘤阳性率为９７％。分别测定血浆去甲肾上腺素和肾上腺素有助于肿瘤位置的判断。对极少数病例，血浆儿茶酚胺正常不能完全排除嗜铬细胞瘤。因生理病理应激使血浆儿茶酚胺升高时，也不要误诊为嗜铬细胞瘤。我国在这方面研究已达到国际先进水平。
The determination of plasma catecholamines is the most sensitive and reliable method for the diagnosis and localization of pheochromocytoma. The diagnostic criteria were: resting plasma norepinephrine> 11.82 pmol/ml and/or epinephrine> 5.46 pmol/ml. The tumors mainly release catecholamines in a continuous diffusion manner. According to their release, they can be classified into multiple secretory types and little or no secretory types. The concentration of plasma catecholamines depends on the secretion of tumors and is not related to tumor size and total catecholamine content. The positive rate of tumor location by vena cava segmentation was 97%. The determination of plasma norepinephrine and epinephrine, respectively, contributes to the judgment of the location of the tumor. In rare cases, plasma catecholamines do not completely exclude pheochromocytoma. Do not misdiagnose pheochromocytoma if you have elevated plasma catecholamines due to physiological and pathological stress. Our research in this area has reached the international advanced level.