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本文报道在上海郊县发现的两个异常血红蛋白病的家系。应用醋酸纤维薄膜电泳从患者血中分离出一种慢速的异常血红蛋白区带,通过肽链柱层析分离、酶解、高压液相层析、氨基酸组分及顺序测定,证实为 Hb Queens(α_(2)~(34L_(e)u→Ar(?))β_2)。
This article reports the families of two abnormal hemoglobinopathies found in suburban Shanghai. A slow abnormal hemoglobin band was isolated from the patient’s blood using acetate thin-film electrophoresis and was confirmed to be Hb Queens (by peptide column chromatography, enzymatic hydrolysis, high pressure liquid chromatography, amino acid composition and sequencing) α_ (2) ~ (34L_ (e) u → Ar (?)) β_2).