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目的探讨应用双水平气道正压通气(BiPAP)对重叠综合征并呼吸衰竭患者的治疗价值。方法将60例重叠综合征并呼吸衰竭患者,随机分为2组。治疗组(30例)在常规治疗基础上(包括氧疗+药物等),加用BiPAP治疗;对照组(30例)仅常规治疗。观察并比较2组在疗效、动脉血气变化、并发症的发生率、住院时间、住院病死率等方面的差异。结果治疗组采用双水平气道正压通气治疗7d后,总有效率、插管率、住院时间等与对照组相比,差异均存在统计学意义(P<0.05)。结论BiPAP治疗重叠综合征并呼吸衰竭比单纯常规治疗效果显著,且并发症少,可减少气管插管率及住院病死率,缩短住院时间,对治疗效果有着重要的影响。
Objective To investigate the therapeutic value of bi-level positive airway pressure (BiPAP) in patients with overlapping syndrome and respiratory failure. Methods Sixty patients with overlap syndrome and respiratory failure were randomly divided into two groups. The treatment group (30 cases) was treated with BiPAP on the basis of routine treatment (including oxygen therapy and drugs); the control group (30 cases) was only routinely treated. The curative effect, arterial blood gas changes, the incidence of complications, length of hospital stay, hospital mortality and so on were observed and compared. Results After treatment with bilevel positive airway pressure for 7 days in treatment group, the total effective rate, intubation rate and hospital stay were significantly different from those in control group (P <0.05). Conclusion BiPAP treatment of overlap syndrome and respiratory failure than the conventional treatment of significant effect, and fewer complications, can reduce tracheal intubation and hospital mortality, shorten hospital stay, the treatment has an important impact.