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STK11是新近发现的一种抑癌基因 ,定位于 19p13 .3 ,STK11的异常被认为不但与黑斑息肉综合征的发病有关 ,还与此类患者恶性肿瘤发病率上升及部分散发肿瘤的发生有关。本文对相关问题进行综述
STK11 is a recently discovered tumor suppressor gene located at 19p13.3 and is considered to be associated not only with the pathogenesis of polyposis syndrome but also with the increased incidence of malignant tumors and the spread of some tumors in these patients . This article reviews the related issues