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目的探讨手术联合辅助治疗对局部复发性直肠癌的疗效。方法选择2010年6月到2011年7月在我院进行治疗的局部复发性直肠癌63例患者作为研究对象,男性为46例,女性为17例,年龄分布为60.57±13.67岁,所有患者均经病理学诊断为复发性直肠癌患者。疾病类型分布研究显示直肠上部为6例,直肠中部为14例,直肠下部为43例。所有患者均签署知情同意书,愿意参加本研究。按照治疗方法不同分为两组,分别为对照组和研究组。结果研究组与对照组治疗效果比较在里急后重、腹部疼痛、血便和血尿均存在统计学意义(P<0.05),研究组瘤体缩小率为100.00%,对照组为72.41%,两组患者比较存在统计学意义(P<0.05),研究组1年生存率为88.24%,对照组为79.31%,两组患者比较存在统计学意义(P<0.05)。结论采用手术联合辅助治疗对局部复发性直肠癌的疗效明确,应加强临床推广。
Objective To investigate the effect of surgery combined with adjuvant therapy on locally recurrent rectal cancer. Methods Sixty-three patients with locally recurrent rectal cancer who were treated in our hospital from June 2010 to July 2011 were selected. There were 46 males and 17 females with a mean age of 60.57 ± 13.67 years. All patients The pathological diagnosis of recurrent rectal cancer patients. Studies on the distribution of disease types showed that the upper rectum was 6 cases, the middle rectum was 14 cases and the lower rectum was 43 cases. All patients signed informed consent, are willing to participate in this study. In accordance with the different treatment methods are divided into two groups, namely the control group and the research group. Results Compared with the control group, there were significant differences in the treatment effects between tebufenozine, abdominal pain, bloody stools and hematuria (P <0.05). The reduction rate of the study group was 100.00% and that of the control group was 72.41% Statistical significance (P <0.05). The 1-year survival rate was 88.24% in the study group and 79.31% in the control group. There was statistical significance between the two groups (P <0.05). Conclusions The curative effect of operation combined with adjuvant therapy on locally recurrent rectal cancer is clear, and clinical promotion should be strengthened.