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目的:观察应用舌下腺刺激术治疗慢性胃炎临床疗效。方法:慢性胃炎患者80例,随机分为两组:治疗组40例,采用舌下腺刺激术治疗,一次约10分钟。剪切黄豆大小一块舌下腺组织,唾液增多,频频咽下,一般不用药物维持;对照组40例,用吗叮啉10mg、3/d,果胶铋1.0g、3/d,口服,疗程两周。观察两组患者消化不良症状积分、生活质量的变化。结果:两组治疗后15d消化不良症状总积分11.67±1.36、15.37±2.01较治疗前26.58±1.81、26.83±1.89降低(P<0.05),治疗后0.5年治疗组7.81±1.10优于对照组25.40±1.92(P<0.05);生活质量治疗组治疗后15d、0.5年,对照组治疗后15d得到明显改善;治疗组治疗后未见不良反应发生。结论:应用舌下腺刺激术治疗慢性胃炎,具有较好疗效,远期疗效治疗组优于对照组,且方法简便、合理、无不良反应,值得进一步研究。
Objective: To observe the curative effect of sublingual gland stimulation on chronic gastritis. Methods: 80 cases of chronic gastritis patients were randomly divided into two groups: 40 cases in the treatment group, the treatment of sublingual gland stimulation, a time of about 10 minutes. Cut a size of soybean sublingual gland tissue, increased saliva, swallow frequently, generally do not have drugs to maintain; control group of 40 cases, with domperidone 10mg, 3 / d, pectin bismuth 1.0g, 3 / d, Two weeks. Observation of two groups of patients with indigestion symptom score, quality of life changes. Results: The total scores of dyspeptic symptoms 15.67 ± 1.36 and 15.37 ± 2.01 after 15 days of treatment in both groups were significantly lower than those before treatment (26.58 ± 1.81,26.83 ± 1.89, P <0.05), and those in the 0.5-year treatment group were 7.81 ± 1.10 better than the control group ± 1.92 (P <0.05). The quality of life in treatment group was significantly improved at 15 days and 0.5 years after treatment, and 15 days after treatment in control group. No adverse reactions occurred in the treatment group after treatment. Conclusion: The application of sublingual gland stimulation in the treatment of chronic gastritis has good curative effect, and the long-term curative effect is better than the control group. The method is simple, reasonable and without adverse reactions and deserves further study.