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目的探讨药师干预对华法林抗凝患者治疗认知度的影响。方法选取2013年10月至2014年8月在我院心血管内科病房住院的口服华法林抗凝患者216例为研究对象,按照病区分为对照组(心内科一病房)和干预组(心内科二病房),对照组由医师及护士介绍华法林抗凝知识,干预组接受药师关于华法林抗凝的用药教育和指导。在出院时,2组患者均填写华法林用药知识评估问卷,对于不能正确回答所有问题的患者,再由药师进行相关信息的补充教育和指导,并比较2组患者的得分差异。结果干预组入选112名患者,对照组入选104名患者,干预组和对照组出院评估问卷得分分别为(10.50±2.24)和(8.08±2.61),2组比较差异有统计学意义(P<0.05)。结论干预组患者对于华法林抗凝治疗的认知度显著高于对照组,证明药师进行药学干预的综合管理模式可提高华法林抗凝患者治疗的认知度。
Objective To investigate the influence of pharmacist intervention on warfarin anticoagulation therapy in patients with cognitive impairment. Methods A total of 216 oral warfarin anticoagulant patients hospitalized in our cardiovascular hospital ward from October 2013 to August 2014 were selected as the research objects. The patients were divided into control group (cardiology and ward) and intervention group (cardiology 2 Ward). The control group was informed of the warfarin anticoagulation knowledge by physicians and nurses. The intervention group received pharmacist education and guidance on warfarin anticoagulation. At the time of discharge, both groups were filled out the warfarin knowledge assessment questionnaire. For those who could not correctly answer all the questions, the pharmacists conducted supplementary education and guidance on the relevant information and compared the scores of the two groups. Results 112 patients were enrolled in the intervention group and 104 patients in the control group. The scores of discharge assessment questionnaire in intervention group and control group were (10.50 ± 2.24) and (8.08 ± 2.61) respectively, there was significant difference between the two groups (P <0.05 ). Conclusion The intervention group’s awareness of warfarin anticoagulant therapy was significantly higher than that of the control group, demonstrating that the pharmacist’s comprehensive management of pharmacological interventions can increase the awareness of warfarin anticoagulation therapy.