报道一种以间苯二酚为起始原料,通过傅-克酰基化、成吡喃环、羟醛缩合、氧化-重排-关环等五步反应,简洁、高效地合成天然吡喃异黄酮Barbigerone及其类似物的方法.该方法不仅原料易得、价格低廉、操作简单、条件温和,而且可得高达24%～30%的总收率. Reported a resorcinol as the starting material, through the Fu-acylation, pyran ring, aldol condensation, oxidation - rearrangement - ring closed five-step reaction, simple and efficient synthesis of natural pyranyl Flavonoid Barbigerone and the like, which not only has the advantages of availability of raw materials, low price, simple operation, mild conditions, but also yields an overall yield of up to 24% to 30%.