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作者研究糖尿病患者血液凝固系统的状况。病人和方法 85例病人分为两组:第1组33例,初次查出糖尿病,没有糖尿病性血管病的临床症状和心血管系统病变;第2组52例,发现糖尿病10年以上,下肢血管病Ⅲ～Ⅳ期,视网膜病Ⅱ期以上,有冠心病症状。对照组为20名健康人。都是男性,年龄25～40岁。测定血小板聚集指标和解聚指标、血纤维蛋白原和纤维蛋白原 B、纤维蛋白原降解产物、抗凝血酶Ⅲ和血浆肝素水平。结果两组病人血小板聚集指标都增高(P<0.01),解聚指标降低(第1组 P<0.05,第2组P<0.001)。两组纤维蛋白原都增高(P<0.001,
The authors studied the condition of the blood coagulation system in diabetic patients. Patients and Methods 85 patients were divided into two groups: 33 cases in group 1, the first detection of diabetes, no clinical symptoms of diabetic vascular disease and cardiovascular disease; group 2 52 cases, found that diabetes more than 10 years, lower extremity blood vessels Disease Ⅲ ~ Ⅳ, retinopathy Ⅱ or more, with coronary heart disease symptoms. The control group of 20 healthy people. Are male, aged 25 to 40 years old. Platelet aggregation index and depolymerization index, fibrinogen and fibrinogen B, fibrinogen degradation products, antithrombin Ⅲ and plasma heparin were measured. Results The platelet aggregation index (P <0.01) and depolymerization index (P <0.05 in the first group and P <0.001 in the second group) increased in both groups. Both fibrinogen were increased (P <0.001,