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冠心病心绞痛的药物治疗在近十年取得了瞩目的进展.硝酸酯、β阻滞剂、慢通道阻滞剂已成为治疗心绞痛的主要药物.心绞痛患者在伴有其他疾病,或应用其他药物有并发症情况下,选用这三类药物,将可取得满意疗效而副作用最少.今介绍心绞痛伴有其它疾病时的药物治疗如下.一、左心衰竭:由于硝苯吡啶可扩张小动脉降低后负荷,加上交感神经张力反射性增加,抵消了其负性变力作用,故对心绞痛伴严重左室功能损害(EF 下降)的患者,本药在慢通道阻滞剂中为首选.硫氮(?)酮可为次选药.硝酸酯由于扩张小静脉,减少了静脉回流,从而心室容量下降,也宜选用.左室功能正常或轻度损害(EF≥40%),可单用硫氮革酮或异搏定.左室功能中度至严重损害(EF<40%),心脏扩大,有充血性心衰
Drug treatment of coronary heart disease has made remarkable progress in the past decade.Nitrates, β blockers, slow channel blockers have become the main drug for the treatment of angina pectoris patients with other diseases, or the use of other drugs Complications, the choice of these three drugs, will be able to obtain satisfactory results with the least side effects. Introduction of angina pectoris associated with other diseases when the drug treatment is as follows: First, left heart failure: Since nifedipine dilated arterioles reduce the load , Coupled with increased reflex sympathetic tone, offset the role of negative variable force, so angina patients with severe left ventricular dysfunction (EF decline), the drug is the first choice in slow-channel blockers.Sulfur and nitrogen ( ?) Ketone can be the second choice drug. Nitrate due to dilatation of small veins, reducing venous return, which decreased ventricular capacity, should also be used. Left ventricular function is normal or mild damage (EF ≥ 40%), Leather ketone or verapamil. Left ventricular function of moderate to severe damage (EF <40%), heart enlargement, congestive heart failure