胰性脑病作为重症急性胰腺炎发展到一定阶段产生神经精神障碍的综合症 ,一直受到临床医师的关注。 194 1年首次由Ｒｏｔｈｅｒｍｉｃｈ[1] 提出胰性脑病的概念 ,发现 8例急性胰腺炎病人出现精神和神经异常 ,定向力障碍、激动、妄想、幻觉甚至意识模糊 ,其中 5例病人脑组织病理 Pancreatic encephalopathy, as a syndrome of neuropsychiatric disorder that develops to a certain stage in severe acute pancreatitis, has been the concern of clinicians. In 1977, for the first time, Rothermich [1] proposed the concept of pancreatic encephalopathy and found that in 8 patients with acute pancreatitis, there were mental and neurological abnormalities, disorientation, agitation, delusions, hallucinations or even vagueness. The brain pathology