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生长激素释放抑制因子(somatostatin ss)是一种肽类激素,由中枢神经系统或周围神经组织合成,它能和靶细胞膜表面的特异性腺苷酸环化酶抑制性受体结合,是生长激素有效的拮抗因子。最近巳有资料表明ss在体外可对Molt-4淋巴细胞和植物血凝素刺激的T淋巴细胞有抑制作用,为此作者进一步探讨了在免疫应答中ss的免疫调节作用。 实验用Wistar大鼠腹腔巨噬细胞(PM)为效
Somatostatin ss is a peptide hormone synthesized by the central nervous system or peripheral nerve tissue that binds to specific adenylate cyclase inhibitory receptors on the surface of target cell membranes and is an effective growth hormone Antagonist. Recent data have shown that ss can inhibit Molt-4 lymphocytes and phytohemagglutinin-stimulated T lymphocytes in vitro. To this end, the authors further explored the immunomodulatory effects of ss on immune responses. Experimental Wistar rat peritoneal macrophages (PM) for the effect