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职业性氟病是无机氟作业工人长期经呼吸、消化道等不同途径摄入过量含氟气体或粉尘,引起的一种以骨骼病变为主的职业性损害。氟引起的斑釉齿及氟骨症已为医学界所熟知,从整体上看,各系统的重要器官组织均可受累。1937年Roholm首次报道作业工人的骨外临床表现,这些非特异性表现被称为“非骨相(或骨前相)慢性氟中毒”。 本病诊断虽突出以骨骼受损为主要依据,但骨外各种表现也是综合分析中必不可少的因素,木文简要综述常见的骨外临床表现对诊断的意义。
Occupational fluorosis is inorganic fluoride workers long-term breathing, digestive tract and other ways of taking excessive fluoride gas or dust intake, caused by a skeletal disease-based occupational damage. Fluoride caused spot glaze teeth and skeletal fluorosis has been well-known to the medical community, from the overall point of view, the system of important organs and tissues can be involved. Roholm was the first to report on the extrahepatic clinical manifestations of working workers in 1937. These nonspecific manifestations are called “non-phaco (or pre-cancerous) chronic fluorosis.” Although the diagnosis of this disease is mainly based on bone damage, but a variety of bone outside the performance of an integrated analysis is also an essential factor, a brief review of the clinical manifestations of bone outside the significance of the diagnosis.