目前国内外对预测青霉素过敏反应,多数采用皮内试验方法,在一定程度上有效地防止了青霉素过敏性休克的发生。但此法仍存在不足之处,如试验时病人等候时间较长,在注射试验时要发生疼痛,少数高敏病人,在进行皮内试验时仍有一定危险性等。因此,国内外不少学者,多年来一直在研究寻找一种安全有效的体外试验方法,用以代替一向沿用的青霉素皮肤试验,如被动转移试验,血清测验方法等,这些方法的阳性率、特异性、可靠性均较皮肤试验为低,操作步骤及备制方法比较复杂,尚不能在临床上推广使用。又有人在研究“试验抗原”,如用青霉噻唑—多赖氨酸 Currently at home and abroad to predict allergic reactions to penicillin, the majority of intradermal test methods, to a certain extent, effectively prevent the occurrence of anaphylactic shock of penicillin. However, this method is still inadequate, such as patients waiting for a longer test time, pain occurs in the injection test, a small number of patients with high sensitivity, there is still some risk in the intradermal test. Therefore, many scholars at home and abroad for many years have been looking for a safe and effective in vitro test method to replace the penicillin skin tests have always been used, such as passive transfer test, serum test methods, the positive rate of these methods, specific Sex, reliability are lower than the skin test, procedures and preparation methods are more complex, not yet in clinical use. Others are studying “experimental antigens,” such as penicillin-polylysine