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细胞凋亡诱导剂作为治疗肿瘤药物已成为新药研发的热点。我们介绍了近年来蒽醌衍生物、皂苷类、类黄酮及萜类化合物作为细胞诱导剂的研究现状及进展,并对其作用机理进行分析和归纳。凋亡诱导剂有希望开发为安全有效的抗肿瘤药物。
Apoptosis inducer has become a hot spot for new drug research and development as an oncology drug. We introduced the recent research status and progress of quinone derivatives, saponins, flavonoids, and terpenoids as cell inducers, and analyzed and summarized their action mechanisms. Apoptosis-inducing agents are promising as safe and effective antitumor agents.