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采用放射免疫方法测定了２１例大肠癌、９例大肠腺瘤性息肉及７例正常人的空腹血清胃泌素水平。结果发现：大肠癌病人空腹血清胃泌素水平明显高于腺瘤病人及正常人（ｐ＜０．０５）；血清胃泌素水平与肿瘤临床分期无关；肿瘤切除后血清胃泌素显著下降（ｐ＜０．０５）。提示血清胃泌素水平与大肠癌生长密切相关。
Radioimmunoassay was used to determine fasting serum gastrin levels in 21 cases of colorectal cancer, 9 cases of large intestine adenomatous polyps, and 7 cases of normal persons. The results showed that fasting serum gastrin levels in colorectal cancer patients were significantly higher than those in adenomas and normal controls (p<0.05); serum gastrin levels were not associated with tumor clinical stage; serum gastrin was significantly reduced after tumor resection ( p<0.05). It is suggested that serum gastrin levels are closely related to the growth of colorectal cancer.