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对三聚氰胺理化性质、肾脏毒性表征进行了描述,并总结了关于三聚氰胺致肾损伤机制的不同研究进展,其中一种观点认为肾损伤是三聚氰胺、三聚氰酸及三聚氰胺-三聚氰酸结晶体共同作用的结果;而另一种观点认为肾损伤与动物肠道细菌,特别是克雷伯菌属细菌的代谢密切相关。
The physical and chemical properties of melamine and the characterization of nephrotoxicity were described. Different research advances on the mechanism of melamine induced renal injury were summarized. One of the views was that the renal injury was caused by the interaction of melamine, cyanuric acid and melamine-cyanuric acid crystals The other view is that kidney damage is closely related to the metabolism of intestinal bacteria in animals, especially Klebsiella bacteria.