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纤溶酶原激活剂抑制物 - 1(plasminogenactiva torinhibitor- 1,PAI - 1)基因不仅与PAI - 1活性有密切的关系 ,而且影响血脂、血糖代谢[1,2 ] 。本研究应用酶切法对冠心病患者PAI - 1启动子区域单核苷酸插入 /缺失 (4G/ 5G)多态性进行分析 ,旨在探讨冠心病患者PAI - 1基因 4G/
The plasminogen activator inhibitor - 1 (PAI - 1) gene is not only closely related to the activity of PAI - 1, but also affects the blood lipid and glucose metabolism [1,2]. In this study, single nucleotide insertions / deletions (4G / 5G) polymorphisms in the PAI - 1 promoter region of patients with coronary heart disease were analyzed by restriction enzyme digestion to explore the role of PAI - 1 gene 4G /