作者对51例病人分3组进行对照研究(每组各17例).H组首先用3000IU肝素,然后每小时持续输注300IU.A组输ATⅢ以保持ATⅢ活性为100%.A+H组用ATⅢ同A组,并首次用肝素1000IU,以后每小时持续输100IU.入院时,用药后30分钟和以后只要病人在监护室每隔4小时均采血标本.3组病人开始ATⅢ活性为52.6±9.7%.两组间或休克第Ⅱ和Ⅲ期间无明显差异.休克第Ⅳ期,ATⅢ活性为35.4±8.5%,明显低于其它休克期 The authors of 51 patients were divided into three groups for control study (17 cases in each group.) H group first with 3000IU heparin, and then continued to infuse 300IU per hour.A group ATOSE AT Ⅲ to maintain the activity was 100% .A + H group AT Ⅲ with the A group, and for the first time with heparin 1000IU, and then continue to lose 100IU per hour after admission, 30 minutes after treatment and after the patient as long as the patient in the custody of the blood samples were collected every 4 hours .3 group began AT Ⅲ activity was 52.6 ± 9.7% .There was no significant difference between the two groups or during the second and third stages of shock.At the third stage of shock, the activity of ATⅢwas 35.4 ± 8.5%, which was significantly lower than other shock stages