1病例介绍患者女,48岁。因“头痛伴发热4 d”于2015年2月12日入院。入院前4 d,患者开始出现持续性头痛,为全头部胀痛,偶有跳痛,阵发性加重,加重时间可持续数小时,与体位无明显关系,不伴有恶心、呕吐等症状,无明显的加重缓解因素。入院前3 d开始出现发热,体温波动在38.2~38.9℃,畏寒,并开始出现咳嗽、咳痰,痰为白色黏液痰,无脓性、血性痰。自行口服“感冒药”治疗,症状无明显 1 case description Female patient, 48 years old. Because “headache with fever 4 d ” was admitted on February 12, 2015. 4 days before admission, patients began to have persistent headache, pain in the whole head, occasional jump pain, paroxysmal aggravation, and the duration of aggravation for several hours. There was no significant relationship with body position and no symptoms such as nausea and vomiting , No significant increase in mitigation factors. Fever occurred 3 days before admission. The body temperature fluctuated between 38.2 and 38.9 ° C, chills, and cough and sputum began to appear. The sputum was white mucus sputum and had no purulent or bloody sputum. Oral “cold medicine” treatment, no obvious symptoms