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目的 :探讨甲状腺特异性抗体检验在多囊卵巢综合征(PCOS)诊断中的临床价值。方法 :选取2014年7月~2015年9月收治的PCOS患者45例为观察组,另选同期行健康体检女性52例为对照组,对两组受检者血清甲状腺特异抗体水平进行测定,比较其特异抗体阳性率。结果 :观察组患者中,血清甲状腺球蛋白抗体阳性表达13例,阳性率为28.89%,对照组血清甲状腺球蛋白抗体阳性表达3例,阳性率为5.77%,观察组显著较高,差异有统计学意义(P<0.05);观察组患者中,血清甲状腺过氧化物酶抗体阳性表达14例,阳性率为31.11%,对照组血清甲状腺过氧化物酶抗体阳性表达5例,阳性率为9.62%,观察组显著较高,差异有统计学意义(P<0.05)。结论 :血清甲状腺特异性抗体同PCOS发生有密切关联,甲状腺球蛋白抗体、甲状腺过氧化物酶抗体在PCOS患者中表达较高,对其进行检验,可为PCOS临床诊断提供重要参考。
Objective: To investigate the clinical value of thyroid-specific antibody test in the diagnosis of polycystic ovary syndrome (PCOS). Methods: Forty-five patients with PCOS admitted to our hospital from July 2014 to September 2015 were selected as observation group and 52 female volunteers were selected as control group during the same period. Serum thyroid-specific antibody levels were compared between the two groups Its specific antibody positive rate. Results: In the observation group, the serum thyroglobulin antibody positive expression was 13 cases, the positive rate was 28.89%. The control group serum thyroglobulin antibody positive expression in 3 cases, the positive rate was 5.77%, the observation group was significantly higher, the difference was statistically significant (P <0.05). In the observation group, serum thyroid peroxidase antibody positive expression in 14 cases, the positive rate was 31.11%, the control group serum thyroid peroxidase antibody positive expression in 5 cases, the positive rate was 9.62% , The observation group was significantly higher, the difference was statistically significant (P <0.05). CONCLUSIONS: Serum thyroid-specific antibodies are closely associated with the development of PCOS. Thyroglobulin antibodies and thyroid peroxidase antibodies are highly expressed in PCOS patients, which may provide an important reference for the clinical diagnosis of PCOS.