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本文采用温针疗法治疗类风湿关节炎（ＲＡ）１６例观察对其血浆亮脑啡肽、白细胞介素Ⅱ、自然杀伤（ＮＫ）细胞活性的影响，探讨温针对ＲＡ疗效与神经内分泌免疫调节机制。温针治疗后，临床取得较满意疗效，证实温针能温通经络、活血化瘀、疏风散寒、消肿止痛。温针治疗前后血浆亮脑啡肽、白细胞介素Ⅱ、ＮＫ细胞活性均有显著性变化，且与临床疗效呈正相关。说明温针的疗效可能与其调节外周血亮脑啡肽和ＲＡ患者机体免疫功能有关。
In this paper, 16 cases of rheumatoid arthritis (RA) were treated with warm acupuncture to observe their effect on the activity of leu-enkephalin, interleukin-Ⅱ and natural killer (NK) cells, and to investigate the effect of warming needle on RA efficacy and neuroendocrine mechanism . Warming needle treatment, clinically more satisfactory results, confirmed that warm needles can Wen Tong Meridian, blood circulation, Shufeng cold, swelling and pain. The activity of leupeptin, interleukin Ⅱ and NK cell in plasma before and after warm needling treatment both had significant changes, which were positively correlated with the clinical curative effect. Description of the efficacy of warm needles may be related to its regulation of peripheral leukoencephalitis and RA patients with immune function.