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化学预防在于阻遏体内的致癌作用。 一、预防剂 主要防止在生活环境和体内由前身物形成致癌剂。大多数亚硝胺和亚硝酰胺均对动物致癌。在酸性溶液或脂溶剂中,亚硝酸易与二级胺化合成亚硝胺,而维生素C和E(α-生育酚)能够分别阻止亚硝化反应。当将含150ppm(10~(-6))NaNO_2的熏猪肉经180℃油煎后,肉内出现100ppb(10~(-9))NPYR(亚硝基吡咯烷)和小量DMN(二甲亚硝胺)。而且已从油烟中挥发95% NPYR和75~
Chemotherapy involves the suppression of carcinogenic effects in the body. First, preventative agents Mainly prevent the formation of carcinogens from the predecessor in the living environment and the body. Most nitrosamines and nitrosamines are carcinogenic to animals. In acidic solutions or lipid solvents, nitrous acid is susceptible to secondary amination to synthesize nitrosamines, while vitamins C and E (alpha-tocopherol) can prevent nitrosation, respectively. When the smoked pork with 150ppm (10-6) NaNO2 was fried at 180°C, 100ppb (10-9) NPYR (nitrosopyrrolidine) and a small amount of DMN appeared in the meat. Nitrosamine). And 95% NPYR and 75~ have been volatilized from soot