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本次年鉴介绍钙离子通道阻断剂镇痛治疗相关文献,包括其作用机制、镇痛效果、合适剂量的选择,特别介绍N型钙通道阻断剂芋螺毒素(Bu8)治疗难治性疼痛和T型钙通道阻断剂Z944治疗神经病理性疼痛的新动向。“,”This yearbook introduced the literatures on analgesic treatment of calcium antagonists in this year, including its mechanism, analgesic effect and the selection of appropriate dosage, and T-type calcium bloker conotoxin (Bu8) in the treatment of refractory pain and N-type calcium bloker Z944 in the treatment of neuropethic pain.