据有关资料统计,到2000年时,65岁以上的老年人将占世界人口总数的16%以上。按照现行标准,大于与等于160/95 mmHg的高血压患者约占老年人总数的一半。老年高血压病人普遍存在外周血管阻力增高,血容积和心输出量降低,脑及肾灌注减少。相当比例的患者还存在着左室肥大,因为心负荷增加而易发生室性异位和猝死。老年人的主动脉和其它主要动脉的血管壁因为钙和胶原质的沉积而逐渐失去弹性,小血管壁的中层可因透明样蜕变而使管腔横断面积和腔/壁比减低,这些变化导致了与年龄相关的血流动力学改变,从而造成外周血管阻力加大。近 According to statistics, by the year 2000, the elderly over the age of 65 will account for more than 16% of the world’s population. By current standards, patients with hypertension greater than or equal to 160/95 mmHg account for about half of the total number of older adults. Peripheral vascular resistance is generally increased in elderly hypertensive patients, decreased blood volume and cardiac output, decreased brain and renal perfusion. A significant proportion of patients also have left ventricular hypertrophy, because of increased cardiac load and prone to ventricular ectopic and sudden death. The walls of the elderly aorta and other major arteries lose their elasticity due to the deposition of calcium and collagen, and the middle wall of the small blood vessel wall can degrade the lumen cross-sectional area and lumen / wall ratio due to the transparent degeneration, resulting in Age-related hemodynamic changes, resulting in increased peripheral vascular resistance. near