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纤维蛋白原缺乏症是罕见的常染色体隐性遗传病,至今文献报道不超过200例。因缺乏纤维蛋白原.表现多脏器出血,神经系统并发症少见,通常为原发性出血,颅内动脉夹层分离尚无报道。作者报道1例纤维蛋白原缺乏症伴发双侧椎动脉夹层分离。 患者女性,28岁。其父母为近亲结婚,与弟弟均被诊断为纤维蛋白原缺乏症。既往有轻微偏头痛史,因月经次数过多而口服避孕药6个月。有时因轻度出
Fibrinogen deficiency is a rare autosomal recessive disease, reported in the literature so far no more than 200 cases. Due to the lack of fibrinogen. Multi-organ manifestations of bleeding, neurological complications rare, usually primary hemorrhage, intracranial artery dissection has not been reported. The authors report 1 case of fibrinogen deficiency associated with bilateral vertebral artery dissection. Patient female, 28 years old. His parents were married relatives, and his brother were diagnosed as fibrinogen deficiency. Past history of a slight migraine, due to excessive menstrual cycles and oral contraceptives 6 months. Sometimes because of light out