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目的观察前列地尔联合介入术治疗不稳定型心绞痛对患者左心房功能的影响。方法将212例不稳定型心绞痛患者随机分为研究组和对照组各106例。所有患者统一给予常规药物及介入治疗,术后研究组给予前列地尔治疗,对照组给予阿托伐他汀治疗。对比观察2组左房最大容积(LAVmax)、左房容积(LAVp)、左房最小容积(LAVmin)、被动排空分数(LAPEF)及主动排空分数(LAAEF)、左房总体排空分数(LAEF)等。结果研究组治疗后LAVmax、LAVp、LAVmin及LAAEF指标均低于对照组,而LAPEF和LA total EF指标均高于对照组,差异均有统计学意义(P<0.05)。结论前列地尔联合介入术治疗不稳定型心绞痛可有效改善患者左心房功能。
Objective To observe the effect of alprostadil combined with interventional therapy on left atrial function in patients with unstable angina pectoris. Methods 212 patients with unstable angina were randomly divided into study group and control group of 106 cases. All patients were given conventional drugs and interventions. The postoperative study group was treated with alprostadil while the control group was treated with atorvastatin. The left atrium volume (LAVmax), left atrium volume (LAVp), LAVmin, LAPEF and LAAEF, left atrial total emptying score LAEF) and so on. Results The LAVmax, LAVp, LAVmin and LAAEF indexes of the study group were lower than those of the control group, while the indexes of LAPEF and LA total EF were higher than those of the control group (P <0.05). Conclusions Alprostadil combined with interventional treatment of unstable angina pectoris can effectively improve left atrial function in patients.