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目的观察中西药联合治疗冠心病心绞痛对患者心电图疗效及血清白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)水平的影响。方法将202例冠心病心绞痛患者随机分为研究组和对照组。分别在2组患者治疗前后观察患者心电图和检测血清IL-1β及TNF-α水平。结果治疗前2组心电图阳性率和血清IL-1β、TNF-α水平比较差异无统计学意义(P>0.05);治疗后2组心电图阳性率和血清IL-1β、TNF-α水平较治疗前降低,且研究组低于对照组,差异有统计学意义(P<0.05)。结论中西药联合治疗冠心病心绞痛患者能有效的降低心电图阳性率和血清IL-1β、TNF-α水平。
Objective To observe the effects of combined treatment of Chinese and Western medicine on patients with electrocardiogram (ECG) and the levels of serum interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in patients with coronary heart disease and angina pectoris. Methods 202 patients with coronary heart disease angina were randomly divided into study group and control group. Electrocardiogram and serum IL-1β and TNF-α levels were observed before and after treatment in two groups of patients. Results The positive rate of electrocardiogram and the level of serum IL-1β and TNF-α in the two groups before treatment were not significantly different (P> 0.05). After treatment, the positive rate of electrocardiogram and the levels of serum IL-1β and TNF- Decreased, and the study group was lower than the control group, the difference was statistically significant (P <0.05). Conclusion Chinese and Western medicine combined treatment of patients with coronary heart disease angina pectoris can effectively reduce the positive rate of electrocardiogram and serum levels of IL-1β, TNF-α.