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目的 探讨鼻内镜引导下低温等离子射频治疗抗凝药相关顽固性鼻出血的疗效. 方法 将52例抗凝药相关顽固性鼻出血患者随机分为试验组和对照组各26例. 对照组采用传统填塞方法进行止血,试验组采用鼻内镜引导下低温等离子射频进行止血. 比较2组患者在治疗后的鼻腔恢复通气时间、鼻腔出血量和鼻黏膜恢复正常时间和临床疗效. 结果 试验组总有效率高于对照组,差异有统计学意义(P<0.05). 试验组鼻腔恢复通气时间、出血量和鼻黏膜恢复正常时间明显短于对照组,差异有统计学意义(P<0.05). 结论 鼻内镜引导下低温等离子射频微创手术对于抗凝药相关顽固性鼻出血的治疗效果较好,患者痛苦小,不良反应少,值得临床推广应用.“,”Objective To observe the clinical effect of temperature-controlled radiofrequency under nasal endoscope in epistaxis related with anticoagulant drug.Methods 52 cases patients with epistaxis related with anticoagulant drug were randomly divided into test group and control group,each of 26 cases.Control group was treated by traditional packing,test group was treated by temperature-controlled radiofrequency under nasal endoscope.After treatment,compared the nasal recovery ven-tilation,nasal bleeding,nasal recovery time and clinical effect of 2 groups.Results The total efficiency of test group was high-er than that of control group,the nasal recovery ventilation,nasal bleeding and nasal recovery time of test group were shorter than those of conrol group,the difference was statistically significant(P<0.05).Conclusion Ttemperature-controlled radio-frequency under nasal endoscope in epistaxis related with anticoagulant drug has an good effect,less pain,fewer adverse reac-tions,worthy of clinical application.