目的:探讨侵袭性思维与自我损耗在工作场所暴力影响临床护士职业倦怠中的作用机制。方法:于2019年5月，用抓取随机球方法，选择河南省、福建省的10个城市为采样城市，采用分层整群抽样方法，抽取22个三甲医院、23个二甲医院的临床护理工作岗位护士作为研究对象进行横断面流行学调查，共纳入1 200名护士。共回收有效问卷1 159份，问卷回收有效率96.6%。采用《工作场所暴力量表》、《事件影响量表》、《自我调节疲劳量表》和《职业倦怠量表》对1 159名临床护士进行调查。采用Harman单因素检验法对问卷所含的项目进行探索性因子分析，用s-n-k进行两两比较分析护士工作场所暴力、侵袭性思维、自我损耗、职业倦怠的人口学特征得分差异。结果:36~50岁临床护士的职业倦怠得分大于19~35岁临床护士，工龄<3年者侵袭性思维、自我损耗得分大于工龄3年及以上者，职业倦怠得分小于工龄3年及以上者；未婚者职业倦怠得分小于已婚者；非在编者侵袭性思维、自我损耗得分大于在编者；三级医院临床护士工作场所暴力、侵袭性思维、自我损耗、职业倦怠得分大于二级医院临床护士；本科及以上者职业倦怠得分大于专科及以下者；手术科室临床护士工作场所暴力、侵袭性思维、自我损耗得分大于非手术科室临床护士；差异均有统计学意义（n P<0.05）。侵袭性思维和自我损耗在工作场所暴力与职业倦怠之间起中介作用，工作场所暴力通过侵袭性思维的单独中介作用、自我损耗的单独中介作用、侵袭性思维-自我损耗的链式中介作用影响职业倦怠（β=0.16、0.08、0.03，95%n CI：0.251~0.190、0.121~0.028、0.050~0.012，n P<0.05）。n 结论:工作场所暴力通过侵袭性思维和自我损耗的单独中介作用以及侵袭性思维和自我损耗的链式中介作用影响临床护士的职业倦怠。“,”Objective:To explore the influence mechanism of intrusive thoughts and ego depletion between effects of workplace violence on burnout sense in clinical nurses.Methods:In May 2019, 10 cities in Henan Province and Fujian Province were selected as sampling cities by the method of grabbing random balls. Using the stratified cluster sampling method, nurses in clinical nursing posts in 22 third class hospitals and 23 second class hospitals were selected as the research objects for a cross-sectional epidemiological survey, including 1200 nurses. A total of 1159 valid questionnaires were collected, and the effective rate was 96.6%. 1159 clinical nurses were investigated by workplace violence scale, event impact scale, self-regulation fatigue scale and job burnout scale. The items contained in the questionnaire were analyzed by exploratory factor analysis with Harman single factor test, and the demographic characteristics of nurses\' workplace violence, invasive thinking, self loss and job burnout were compared and analyzed with s-n-k.Results:Those with less than 3 years of service, those with more than 3 years of aggressive thinking and self loss score, and those with less than 3 years of job burnout score; The score of job burnout of unmarried was lower than that of married; The scores of invasive thinking and self loss of non editors were higher than those of current editors; The scores of workplace violence, aggressive thinking, self loss and job burnout of clinical nurses in tertiary hospitals were higher than those in secondary hospitals; The score of job burnout of undergraduate and above is higher than that of junior college and below; The scores of workplace violence, aggressive thinking and self loss of clinical nurses in surgical departments were higher than those in non-surgical departments; The job burnout score of those aged 36 and above was higher than that of those aged <36, The difference was statistically significant ( n P< 0.05) . Aggressive thinking and self attrition played a mediating role between workplace violence and job burnout. Workplace violence affected job burnout through the single mediating role of aggressive thinking, the single mediating role of self attrition, and the chain mediating role of aggressive thinking self attrition (β=0.16、0.08、0.03, 95%n CI: 0.251~0.190、0.121~0.028、0.050~0.012, n P<0.05) .n Conclusion:Workplace violence affects burnout sense through the independent mediating role of intrusive thoughts and ego depletion and the chain mediating role of intrusive thoughts and ego depletion in clinical nurses.