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目的 :探讨超声引导下植入式微波热场的空间分布及其不同参数条件下的变化规律。方法 :分别对 10头猪进行了 45个点和 2 0例肝癌患者进行了 46个点次的温度测量并与计算机模拟微波热场温度进行了对比分析。结果 :动物实验和肝癌患者测温结果与计算机模拟结果有较好一致性的 (温度差别≤ 6℃分别占 75 .6 %和 84.8%。血流灌注是影响组织温升最重要的因素 ,肝癌包膜因素对温升也有较大的影响。结论 :动物实验和临床研究结果表明用有限元的方法建立的计算机模拟热场是准确和可靠的 ,该方法的应用为肝癌治疗中微波热场的精确调控和预测奠定了理论和技术基础。
Objective: To investigate the spatial distribution of implantable microwave thermal field guided by ultrasound and its variation under different parameters. Methods: The temperature of 46 points in 45 pigs with 45 points and 20 liver cancer patients were measured and compared with the computer simulation of microwave thermal field temperature. Results: The results of temperature measurement in animal experiments and liver cancer patients were in good agreement with the results of computer simulation (temperature difference ≤ 6 ℃ accounted for 75.6% and 84.8%, respectively.) Hemoperfusion was the most important factor affecting tissue temperature, Envelope factors also have a greater impact on temperature rise.Conclusion: Animal experiments and clinical studies have shown that the computer simulation of the thermal field established by the finite element method is accurate and reliable, and the application of the method is the microwave thermal field in the treatment of liver cancer Precise regulation and forecasting laid the theoretical and technical foundation.