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目的：探讨屈光参差性弱视和屈光不正性弱视的发病机理。方法：用幼猫视觉发育期单眼和双眼慢性阿托品化的方法塑造上述两种动物模型，成年后摘除外膝体，进行ＧｏｌｇｉＣｏｘ染色，观察计算背侧外膝体（ｄｏｒｓａｌｌａｔｅｒａｌｇｅｎｉｃｕｌａｔｅｎｕｃｌｅｕｓ，ｄＬＧＮ）Ａ１层的胞体截面积的树突野的有关参数。结果：实验动物ｄＬＧＮＡ１层的ｃｌａｓｓ１和ｃｌａｓｓ２细胞胞体的截面积和树突野各参数的改变均为：单眼阿托品化眼所支配的细胞与正常眼的差异均有显著性，双眼阿托品化眼与正常眼差异有显著性，单眼阿托品化眼与双眼阿托品化眼之间差异无显著性。结论：屈光参差性弱视与屈光不正性弱视可能具有相似的发病机制。
Objective: To investigate the pathogenesis of anisometropic amblyopia and anisometropic amblyopia. Methods: The two animal models were established by monocular and binocular atropisolization during the visual developmental period of the kittens. The adult knee joints were excised and the GolgiCox staining was performed. The cell bodies of the dLBN layer were observed and calculated. Cross-sectional area of the dendrite related parameters. Results: The changes of the cross-sectional area of dendritic cells and the cell body of class1 and class2 cells in the dLGNA1 layer of experimental animals were as follows: the differences between the cells dominated by monocular atropine and normal eyes were significant, There was significant difference between the eyes. There was no significant difference between atropine and monocular eyes. Conclusion: Ametropic amblyopic and refractive amblyopia may have a similar pathogenesis.