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据统计,对比剂肾病占急性肾功能不全病人的10％,发病机制可能是由于对比剂直接损伤肾小管或引起肾血流量减少所致。为研究糖尿病病人发生对比剂肾病的危险因素,作者观察了19例有糖尿病肾病的非胰岛素依赖型糖尿病,年龄56～68岁。进行过冠状动脉造影、血管造影和静脉尿路造影。所有病例均口服降糖药,16例有高血压病需用降压药,均无尿路感染和心力衰竭。 结果显示,6例(31.％)发生了对比剂肾病者为基本组,造影后1～5天(即氮血症高峰期)血清肌酐
According to statistics, contrast agent nephropathy accounted for 10% of patients with acute renal insufficiency, the pathogenesis may be due to contrast agents directly damage the renal tubules or caused by decreased renal blood flow. To investigate the risk factors for developing contrast-induced nephropathy in diabetic patients, we examined 19 non-insulin-dependent diabetic patients with diabetic nephropathy, aged 56-68 years. Coronary angiography, angiography and intravenous urography were performed. All cases were oral hypoglycemic agents, 16 cases of hypertension need antihypertensive drugs, no urinary tract infection and heart failure. The results showed that 6 patients (31.%) occurred in patients with contrast-induced nephropathy as the basic group, 1 to 5 days after angiography (peak of azotemia) serum creatinine