对３０例尿毒症患者脑干听觉诱发电位（ＢＡＥＰ）检测，观察到用促红细胞生成素（ＥＰＯ）治疗前，患者ＢＡＥＰ各波潜伏期（ＰＬ）及峰间潜伏期（ＺＰＬ）普遍延长，治疗１２周后，神经系统症状得到改善，ＰＬ及ＺＰＬ相应缩短，与治疗前相比差异显著（Ｐ＜０．０５）。而非血透非ＥＰＯ组及单纯血透组，脑干电位无明显改善。相关分析显示，尿毒症患者ＢＡＥＰ异常与Ｈｂ、ＲＢＣ呈负相关，与尿素氮（ＢＯＮ）、肌酐（Ｓｃｒ）无明显相关性。 The brainstem auditory evoked potentials (BAEP) were measured in 30 patients with uremia. Before the treatment with erythropoietin (EPO), the BAEP latency and the peak latency (ZPL) were generally prolonged. After 12 weeks of treatment, Neurological symptoms were improved, PL and ZPL shortened correspondingly, and the difference was significant compared with that before treatment (P <0.05). Non-hemodialysis EPO group and hemodialysis group, no significant improvement in brain stem potential. Correlation analysis showed that abnormal BAEP in uremic patients was negatively correlated with Hb and RBC, but not with BON and Scr.