~(99m)Tc-DTPA肾动态显像在小儿肾盂积水中的应用

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目的探讨99mTcDTPA肾动态显像诊断小儿肾盂积水的临床价值。方法常规99mTcDTPA肾动态显像方法,15分钟后静脉注射速尿,共检查肾盂积水患儿45例,其中7例作手术前后比较。定量分析指标包括:肾血流灌注率(BPR),高峰摄取率(PUR),半排泄时间(T1/2)。结果①BPR随积水程度加重而明显下降,重度积水为168%±68%,中度积水为351%±69%,轻度积水为406%±92%。PUR在重度积水时为216%±129%。②7例患儿中6例术后BPR明显升高。术前、术后T1/2分别为413±204和229±119分钟。术后T1/2明显改善。结论①BPR可正确反映肾盂积水和肾功能受损程度,两者呈正相关;②术后肾功能改善情况和速尿介入能正确判断集尿系统有无梗阻存在 Objective To investigate the clinical value of 99mTcDTPA renal dynamic imaging in the diagnosis of pediatric hydronephrosis. Methods Conventional 99mTc DTPA renal dynamic imaging method, intravenous furosemide 15 minutes later, a total of 45 cases of hydronephrosis in children, of which 7 were compared before and after surgery. Quantitative analysis of indicators include: renal perfusion rate (BPR), peak uptake rate (PUR), semi-excretion time (T1 / 2). Results (1) The BPR decreased significantly with the increase of waterlogging, with severe water loss of 168% ± 68%, moderate water loss of 351% ± 69% and mild water loss of 406% ± 9  2%. PUR was 21.6% ± 12.9% in severe waterlogging. ② 7 cases of children with postoperative BPR significantly increased. Preoperative and postoperative T1 / 2 were 413 ± 204 and 229 ± 119 minutes, respectively. T1 / 2 after operation was significantly improved. Conclusion ①BPR can correctly reflect the degree of hydronephrosis and impaired renal function, the two are positively correlated; ② postoperative improvement of renal function and furosemide intervention can correctly determine the presence or absence of obstruction urine collection system
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