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采用ＥＬＩＳＡ法测定６０例冠心病患者和２０例健康人血浆Ｄ－二聚体（ＤＤ）的含量。结果显示：（１）急性心肌梗塞（ＡＭＩ）组和陈旧性心肌梗塞（ＯＭＩ）组血浆平均ＤＤ值分别与对照组相比有显著性差异（Ｐ＜０．００１，Ｐ＜０．０１）。（２）ＡＭＩ组的血浆平均ＤＤ伍分别与ＯＭＩ组、心绞痛组、隐性冠心病组相比也有显著性差异（Ｐ＜０．００５）。（３）冠心病组中共有３８例血浆ＤＤ含量异常增高，其中５８％为心肌梗塞患者。ＡＭＩ组和ＯＭＩ组血浆ＤＤ异常申分别与对照组相比，有显著性差异（Ｐ＜０．００５，Ｐ＜０．０２５）。提示心肌梗塞患者体内纤溶系统处于活跃状态。因此，血浆ＤＤ含量的测定可作为心肌梗塞诊断的辅助指标之一，尤其是ＡＭＩ患者血浆ＤＤ含量升高更为明显且阳性率也最高。
The plasma levels of D-dimer (DD) in 60 patients with coronary heart disease and 20 healthy people were measured by ELISA. The results showed that: (1) The mean plasma DD values in acute myocardial infarction (AMI) group and old myocardial infarction group (OMI) were significantly different from those in control group (P <0.001, P <0.01). (2) The average plasma levels of DD in AMI group were also significantly different from OMI group, angina pectoris group and recessive coronary heart disease group (P <0.005). (3) A total of 38 cases of coronary heart disease in patients with abnormal plasma levels of DD increased, of which 58% of patients with myocardial infarction. There were significant differences in plasma DD abnormalities between AMI group and OMI group as compared with the control group (P <0.005, P <0.025). Tip in patients with myocardial infarction in vivo fibrinolytic system in an active state. Therefore, the determination of plasma DD levels can be used as a secondary indicator of myocardial infarction diagnosis, especially in patients with AMI plasma DD levels increased more clearly and the highest positive rate.