本世纪中期以来,心血管疾病已成为西方国家最常见的死亡原因,其中又以急性心肌梗塞(AMI)为首。60年代中期,由于建立了重症监护病房,心律失常得以及时发现和治疗,使AMI的早期死亡率有所下降;70年代,由于药物能降低心肌氧耗,AMI的死亡率又有所下降;80年代,由于静脉溶栓的广泛应用,AMI的死亡率再次下降;目前,急诊PTCA又使AMI的早期死亡率有所下降,而各种药物的最佳组合又使其进一步下降。 AMI的治疗方法很多,下面着重介绍溶栓治疗。 Cardiovascular disease has become the most common cause of death in western countries since the middle of this century, with AMI as the leading cause of death. In the mid-1960s, due to the establishment of an ICU, arrhythmias were promptly detected and treated, leading to a decrease in the early mortality rate of AMI. In the 1970s, AMI mortality declined due to the drug’s ability to reduce myocardial oxygen consumption. 80 In the early 1990s, the mortality rate of AMI dropped again due to the widespread use of intravenous thrombolysis. At present, the emergency PTCA reduced the early mortality rate of AMI and further reduced the optimal combination of various drugs. AMI treatment of many, the following focuses on thrombolytic therapy.