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细胞凋亡是一种自主性的细胞主动死亡,其触发因素众多,提示内部存在着不同的启动机制和运行通路;细胞凋亡与程序性细胞死亡二者各自蕴含的“程序性”具有不同的内涵,这两个概念有必要相互独立地使用下去。细胞凋亡是机体的一种正常生理机制,生理状态下参与调节体内正常细胞的更新和异常细胞的清除,而在病理状态下异常的凋亡又与肿瘤等多系统疾病的发生发展密切相关。
Apoptosis is an autonomous cell death, its triggering factors are numerous, suggesting that there are different internal promoter mechanisms and operational pathways; apoptosis and programmed cell death are contained in each of the “program” has a different Connotation, these two concepts need to be used independently of each other. Apoptosis is a normal physiological mechanism of the body. Physiologically, it is involved in the regulation of normal cell regeneration and abnormal cell clearance. Abnormal apoptosis in pathological conditions is closely related to the occurrence and development of multiple system diseases such as tumors.