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目的分析腹腔镜卵巢囊肿剔除术对卵巢功能的影响,总结治疗经验。方法对142例符合筛选条件腹腔镜卵巢囊肿剔除术患者进行前瞻性研究,分析性激素水平变化情况、排卵功能恢复情况。结果未发生术中损伤;手术时间43~94 min,平均手术时间(70±14)min,出血量10~60 m L、平均出血量(33.4±17.2)m L;第6个月月经正常率95.1%高于第3个月的88.0%,差异具有统计学意义(P<0.05);术后3个月恢复排卵44.37%,低于术后6个月恢复排卵83.10%,差异具有统计学意义(P<0.05):术后1周,FSH、LH高于术前,E2低于术前,术后3个月FSH、LH高于术前且低于术后1周,术后3个月E2低于术前、高于术后1周,差异具有统计学意义(P<0.05)。结论腹腔镜卵巢囊肿剔除术可影响卵巢功能,尽管性激素指标多在正常水平以内,但有部分患者无法恢复排卵功能,出现月经紊乱。
Objective To analyze the effect of laparoscopic ovarian cyst excision on ovarian function and to summarize the experience of treatment. Methods A total of 142 patients undergoing laparoscopic ovarian cyst excision were prospectively studied, and the changes of sex hormone levels and ovulation recovery were analyzed. Results No intraoperative injury occurred. The operation time ranged from 43 to 94 minutes, with an average operation time of 70 ± 14 min, an amount of bleeding of 10 to 60 m L and an average amount of blood loss of 33.4 ± 17.2 m L. (95.1%) was higher than that of the third month (88.0%), the difference was statistically significant (P <0.05); 3 months after the operation, the ovulation recovery was 44.37%, which was 83.10% less than the 6 months after the operation, the difference was statistically significant (P <0.05). FSH and LH were higher than preoperative one week after operation and E2 was lower than preoperative and postoperative three months FSH and LH were higher than preoperative and lower than postoperative one week and three months postoperatively E2 lower than preoperative, higher than 1 week after surgery, the difference was statistically significant (P <0.05). Conclusions Laparoscopic ovarian cyst excision can affect ovarian function. Although the indexes of sex hormone are mostly within the normal level, some patients can not restore the ovulation function and have menstrual disorders.