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我科于1994年1月～1996年10月采用赛庚啶治疗小儿哮喘性支气管炎及毛细支气管炎43例,报告如下。1 一般资料 按最新儿童哮喘诊断标准,随机分成观察组43例(男29例,女14例);对照组33例(男22例,女11例),年龄2个月～8岁。入院时平均病程x±s为2.45 d±1.02 d,对照组 2.91d±1.33 d,差异不显著,(P>0.05)。患儿均有发热、咳喘、呼气性呼吸困难,肺部有哮鸣音及粗湿性罗音。有湿疹、鼻炎、荨麻疹等过敏史者53例(70.0％),家族中有哮喘史者11例(14.5％)。两组常规剂量同时应用抗炎、止咳、解痉等药物,观察组加用赛庚啶片 0.2 mg/(kg·d),tid,po,哮鸣音消失后停药。
Division I in January 1994 ~ October 1996 using cyproheptadine treatment of asthmatic bronchiolitis and bronchiolitis in 43 cases, the report is as follows. 1 General information According to the latest diagnostic criteria for children with asthma, were randomly divided into observation group of 43 cases (29 males and 14 females); control group of 33 patients (22 males and 11 females), aged 2 months to 8 years. The average duration of admission x ± s 2.45 d ± 1.02 d, control group 2.91 d ± 1.33 d, the difference was not significant (P> 0.05). Children have fever, cough, exhaled breathlessness, wheezing lungs and rough wet rales. 53 cases (70.0%) had history of allergies such as eczema, rhinitis and urticaria, and 11 cases (14.5%) had history of asthma in the family. The two groups of conventional dose at the same time the application of anti-inflammatory, cough, spasm and other drugs, the observation group plus cyproheptadine 0.2 mg / (kg · d), tid, po, wheeze disappeared after discontinuation.