寒冷病(Cryopathies)首先由 Ritzman 提出,是指对寒冷敏感为明显特点的一类疾病。在这类疾病中寒冷是引起冷沉淀的原因,但这类疾病中各种疾病的病机并不相同。本文就寒冷病作一综述。一、冷球蛋白血症(简称冷球血症)分类:冷球蛋白血症又称冷免疫球蛋白血症。其血清蛋白质或蛋白复合体在低温时能产生沉淀,从而产生的临床表现。根据免疫化学和病因,本病分为二 Cryopathies, first proposed by Ritzman, are a group of diseases that are clearly characteristic of the cold. In such diseases, cold is the cause of cold precipitation, but the pathogenesis of various diseases in these diseases is not the same. This article reviews cold diseases. First, cryoglobulinemia (referred to as cold syndrome) Category: cryoglobulinemia, also known as cold immunoglobulinism. Its serum protein or protein complexes can precipitate at low temperatures, resulting in clinical manifestations. According to immunochemistry and etiology, the disease is divided into two