Brain abscess in children,experience of Mashad University

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Objective:Brain abscesses continue to pose a problem in neurosurgery,and it is a serious life-threatening complication for several diseases.The objective of this research was to look at the clinical profile of children suffering from brain abscess,predisposing conditions,microbiology and outcome of these patients.Methods:Ninety children aged less than 15 years were reviewed.The clinical presentation,predisposing factors,diagnosis,management and outcome were noted.There were 56(62.2%)males and 34(37.7%)females.The mean age of presentation was 5.7±4.2 years.Results:The mean duration of illness at the time of presentation was 10.6 ±12.4 days.Typically patients presented with fever,vomiting,headache,neurological deficit,and seizures.The predisposing conditions found were cyanotic congenital heart disease in 18(20 %)of children,meningitis in 6(6.7 %),Otitis or mastoiditis in 32(35.5 %),Head trauma in 6(6.7 %),previous intracranial surgery in 8(8.8 %)and no underlying cause was found in 22(24.4 %)children.The most common microbe in children with cyanotic congenital heart disease was of the Streptococcus group(54 %).Computerized tomography confirmed the diagnosis and the most common location of the abscess was the parietal lobe of the cerebral hemisphere.That abscesses were larger than 2 cm in diameter where aspirated surgically.Excision was performed for eight children.Six children expired,two due to intracranial bleeding and the others due to severe cerebral edema and tentorial herniation.Complications were observed in 11 children out of which six had squeal and five had hemiparesis.Conclusion:Attention to hygiene of mouth and teeth in infant and child patients with cyanotic heart disease is very important in prevention of infectious brain diseases.We must also pay attention to ear-nose-throat diseases of children.That is very important the patients be examined again after treatment because of finding and treatment of unknown otitis and chronic sinusitis. Objective: Brain abscesses continue to pose a problem in neurosurgery, and it is a serious life-threatening complication for several diseases. The objective of this research was to look at the clinical profile of children suffering from brain abscess, predisposing conditions, microbiology and outcome of these patients. Methods: Ninety children aged less than 15 years were were reviewed. The clinical presentation, predisposing factors, diagnosis, management and outcome were all patients were.There were 56 (62.2%) males and 34 (37.7%) females. of presentation was 5.7 ± 4.2 years. Results: The mean duration of illness at the time of presentation was 10.6 ± 12.4 days.Typically patients presented with fever, vomiting, headache, neurological deficit, and seizures. predisposing conditions found were cyanotic congenital heart Of the children with meningitis in 6 (6.7%), Otitis or mastoiditis in 32 (35.5%), Head trauma in 6 (6.7%), previous intracranial surgery in 8 was found in 22 (24.4%) children.The most common microbe in children with cyanotic congenital heart disease was of the Streptococcus group (54%). Computerized tomography confirmed the diagnosis and the most common location of the abscess was the parietal lobe of the cerebral hemisphere. abscesses were larger than 2 cm in diameter where aspirated surgically.Excision was performed for eight children.Six children expired, two due to intracranial bleeding and the others due to severe cerebral edema and tentorial herniation. Complications were observed in 11 children out of which six had squeal and five had hemiparesis.Conclusion: Attention to hygiene of mouth and teeth in infant and child patients with cyanotic heart disease is very important in prevention of infectious brain diseasess.We must also pay attention to ear-nose-throat diseases of children. That is very important the patients be examined again after treatment because of finding and treatment of unknown otitis and chronic sinusitis.
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