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目的:将蒙成药陶匹浪-7汤进行剂型改革制成胶囊剂,便于临床应用。方法:采用正交试验法对黄连中小檗碱与瞿麦中皂甙的提取工艺进行筛选,并制成半浸膏粉胶囊剂。结果:黄连中小檗碱的最佳提取工艺为用02%硫酸-70%乙醇回流提取,第一次7倍量25h,第二次5倍量15h。瞿麦中皂甙的最佳提取工艺为70%乙醇回流提取,第一次16倍量25h,第二次12倍量20h。结论:该胶囊制备工艺操作简单,成本较低,对生产具有参考价值
Objective: Mongolian pottery waves Lang -7 soup for the formulation of capsules made for ease of clinical application. Methods: The extraction process of berberine and quercetin from berberine in Coptis chinensis Franch was screened by orthogonal test and made into semi-extract powder capsule. Results: The optimal extraction process of berberine in Coptis chinensis was extracted with 02% sulfuric acid and 70% ethanol, the first 7 times of 25h and the second 5 times of 15h. The best extraction technology of Qu Mai saponins was 70% ethanol reflux extraction, the first 16 times the amount of 2 5h, the second 12 times the amount of 2 0h. Conclusion: The capsule preparation process is simple, low cost and has reference value for the production