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目的 :评价龙牡安神颗粒治疗注意缺陷多动障碍(attention-defi cit hyperactivity disorder,ADHD)疗效、改善症状情况、安全性。方法 :2014年2月~2015年8月,观察组与对照组各纳入患者28例,均给予益智宁神颗粒治疗,对照组给予安慰剂,观察组联合龙牡安神颗粒,对比相关指标。结果:观察组控制+显效率57.1%高于对照组35.7%,治疗后观察组与对照组SNAP-Ⅳ量表评分、家长问询Connrs积分、多动指数低于治疗前,观察组低于对照组,差异具有统计学意义(P<0.05);观察组出现1例呕吐,对照组未见不良反应,差异无统计学意义(P>0.05)。结论 :龙牡安神颗粒治疗ADHD疗效好,可有效减轻症状,安全可靠。
Objective: To evaluate the efficacy of Longmu Anshen Granule in the treatment of attention-deficient hype hyperactivity disorder (ADHD) and to improve the symptoms and safety. Methods: From February 2014 to August 2015, 28 patients in the observation group and the control group were treated with Yizhiningshen granule. The control group was given placebo and the observation group was given Longmu Anshen granule in comparison with the related indexes. Results: The control + markedly effective rate in observation group was 57.1% higher than that in control group (35.7%). After treatment, SNAP-Ⅳ scale, parental inquiry Connrs score and hyperactivity index were lower in observation group and control group than those in control group Group, the difference was statistically significant (P <0.05); 1 case of vomiting in the observation group, no adverse reactions in the control group, the difference was not statistically significant (P> 0.05). Conclusion: Longmu Anshen Granules is effective in treating ADHD, which can effectively relieve the symptoms and is safe and reliable.